The kit is designed for detection of mutations associated with drug resistance in the tuberculosis complex mycobacteria DNA with determination of sensitivity to the First-line chemotherapy drugs and their analogues.
• The result of the assay allows for choosing of an appropriate therapy for patients with the confirmed diagnosis of pulmonary and extrapulmonary tuberculosis.
• The resistance of the tuberculosis complex mycobacteria to rifampicin (rpoB), isoniazid (katG and inhA) and their analogues is determined.
✅The kit is compatible with almost all RT-PCR devices.
Detection Method | Real-Time PCR (Melting Curves) |
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Test Format | Qualitative Multiplex |
Sample | Sputum, bronchoalveolar lavage, bronchial washing, gastric washing, pleural Fluid, blood, urine, microbiological cultures, prostate secretion, tissue (biopsy and surgical) material, synovial Fluid, pericardial Fluid and cerebrospinal Fluid |
Detection Of Mutations |
rpoB: Polymorphisms of codons 510–533, D516V, D516Y, codon 526, L533R, L533P, S531L katG: S315T, S315N, S315R, S315I polymorphisms inhA: C-15T polymorphism, and polymorphisms of the region -20 to +6 are also detected, but not differentiated |
Number of Reactions | 96 Reactions |
Test Time | 125~150 Minutes |
Recommended Extraction Kit | NA-Extra-M |