MTB-RESIST-II-TEST – Tuberculosis Drug Resistance Detection Kit
The kit is designed to detect polymorphisms associated with drug resistance to second-line chemotherapy drugs (aminoglycosides and fluoroquinolones) and their analogues. The result of the assay makes it possible to choose the appropriate therapy for patients with a confirmed diagnosis of pulmonary and extrapulmonary tuberculosis.
• The resistance of the Mycobacterium tuberculosis complex to aminoglycosides (rrs and eis gene polymorphisms) and fluoroquinolones (gyrA and gyrB gene polymorphisms) and their analogs is detected.
✅The kit is compatible with almost all RT-PCR devices.
Features & Characteristics
| Detection Method | Real-Time PCR (Melting Curves) |
|---|---|
| Test Format | Qualitative Multiplex |
| Sample | Sputum, bronchoalveolar lavage, bronchial washing, gastric washing, pleural Fluid, blood, urine, microbiological cultures, prostate secretion, tissue (biopsy and surgical) material, synovial Fluid, pericardial Fluid and cerebrospinal Fluid |
| Detection Of Mutations |
rrs: 1401A>G, 1402C>T and 1484G>T eis: C-14G, C-14T, C-12T, G-10C, G-10A and G-37T gyrA: p.G88C, p.A90V, p.S91P, p.D94G, p.D94N, p.D94H, p.D94A and p.D94Y gyrB: p.D461H, p.D461N, p.N499D, p.E501V and p.A504V |
| Number of Reactions | 96 Reactions |
| Test Time | 125~150 Minutes |
| Recommended Extraction Kit | NA-Extra-M |
Test Method
